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Best Weight Loss Supplements for Men

Weight gain is an inevitable occurrence as our bodies go through changes daily.

Written by Liposet Staff

Updated on

Best Weight Loss Supplements Weight Loss Supplements/Shutterstock

Weight gain is an inevitable occurrence as our bodies go through changes daily.

Our sedentary lifestyle is also a key reason that we keep on gaining pounds without realizing it.

To counter this, there are multiple men’s weight loss products that promise to help shed this extra weight.

Most weight loss supplements target boosting metabolism, /lieaking down fat deposits, suppressing appetite, and enhancing energy levels.

While these claims sound impressive, not all of the products can live up to their promises.

Moreover, some weight loss supplements for men often feature ingredients that have little to no scientific backing, meaning their effectiveness is questionable.

Luckily, there are genuine products in the market that have shown exceptional results.

These supplements often contain effective ingredients such as caffeine, green tea, vitamin B12, cayenne pepper, and Yohimbe among others.

In this comprehensive review, we feature the best weight loss supplements for men, a “how to buy guide”, and alternative products you can try.

What Are the Best Weight Loss Supplements for Men?

The supplements we feature here are backed by scientific research, they include:


Caffeine is one of the most commonly used stimulants in the world. It is known to increase energy levels and alertness, but does it promote weight loss?

A meta-analysis published in the Critical Reviews in Food Science and Nutrition journal concluded that “caffeine intake might promote weight, BMI, and body fat reduction.”

Another study published by the European Journal of Clinical Nutrition provided a correlation between caffeine and successful weight loss maintenance.

Researcher D. Icken, of the Department of Psychosomatic Medicine and Psychotherapy, Hannover Medical School, and team established that “consumption of caffeinated beverages might support weight loss maintenance” as seen in the 494 weight loss maintainers under study.

  • May promote weight, BMI, and fat reduction

  • May help with healthy weight maintenance

  • May enhance energy levels and improve mood

  • May keep users alert and focused on their activities

  • Can cause side effects such as jitters, insomnia, and increased heart rate

  • Can cause caffeine dependency

Best for:

Users who have no caffeine sensitivity.

Final verdict:

Caffeine has the potential as a weight loss supplement based on scientific research.

Its positive effects outweigh the negative symptoms, making it worth a try.

Green Tea

Green tea has been used since time immemorial for weight loss.

It is usually available in the form of tea leaves or powdered concentrate. Green tea is rich in caffeine and polyphenol catechins which are known to promote weight loss.

A 2013 clinical trial published in the BMC Complementary Medicine and Alternative Medicine journal, examined the effects of green tea extract supplements on overweight and obese women and found it to be effective.

Researcher Lin-Huang Huang and team discovered that green tea increased leptin and reduced LDL (low-density lipoprotein or “bad cholesterol”) in obese women after 6 weeks of treatment.

In Advances in Nutrition, researchers Adrian B. Hodgson, Rebecca K. Randell, and Asker E. Jeukendrup tested the effect of green tea extract (GTE) on fat oxidation at rest and during exercise.

They concluded that longer-term GTE intake may have implications on fat metabolism both at rest and during exercise.

However, more studies are required to ascertain these results and shed light on the underlying mechanisms of the process.

  • May promote weight loss, reduction in BMI, and lowered waist circumference

  • May provide other health benefits including antimicrobial, anti-cancer, anti-inflammatory, and antioxidant properties

  • May boost energy

  • May suppress appetite

  • May elevate mood

  • May have a small impact on weight loss

  • May cause side effects such as constipation, nausea, stomach discomfort, and a spike in blood pressure

  • Contains caffeine

Best for:

Users looking to get slimmer while enjoying other health benefits of green tea.

Caffeine-sensitive users can also take green tea as its caffeine content is low.

Final Verdict:

Green tea has the potential to cause weight loss.


Magnesium, an essential element, is important for bone health, muscle recovery, as well as sleep and relaxation.

Its anti-inflammatory properties are claimed to have implications for weight loss.

A systematic review published in the Critical Reviews in Food Science and Nutrition found a significant reduction in BMI and waist circumference following magnesium supplementation.

Similarly, researcher Liping Lu and team concluded that “magnesium intake is inversely associated with incidence of obesity.” In this study, intake of foods rich in magnesium such as whole grains, nuts and seeds, dark green vegetables, and legumes, was associated with a lower incidence of obesity.

  • May help reduce BMI and waist circumference

  • May improve bone health and sleep pattern

  • May elevate mood and provide support for depressive symptoms

  • May cause nausea, vomiting, and diarrhea

  • May not cause significant weight loss

Best for:

Obese men as it improves sleep disorders and depressive symptoms which can contribute to obesity.

Final verdict:

While this supplement has the potential to cause weight loss, it seems that it is more beneficial for men with obesity.


High-protein meals are claimed to have the capacity to reduce body weight, fat mass, and weight gain while preserving lean mass.

A 2020 study published in the Journal of Obesity & Metabolic Syndrome discovered that a high-protein diet increased thermogenesis, blood amino acid concentration, ketogenesis, and satiety.

According to researchers Jaecheol Moon and Gwanpyo Koh from the Department of Internal Medicine, Jeju National University Hospital, “consuming more protein than the recommended dietary allowance not only reduces body weight but also enhances body composition by decreasing fat mass while preserving fat-free mass.”

  • May reduce body weight and consistent weight gain

  • May reduce fat mass while preserving fat-free mass,/

  • May induce and maintain ketogenesis

  • May increase satiety

  • Protein supplements are available in multiple forms such as bars, gummies, shakes, and powders

  • More protein intake can cause digestive issues such as constipation and diarrhea

  • More research is required to prove the potency of protein supplements

Best for:

Men looking to; increase their protein intake, maintain a healthy weight, and build and preserve muscle.

Final verdict:

High protein intake can cause weight loss, lean mass preservation, and preventing weight gain.


Dietary fiber is found in fruits, whole grains, vegetables, beans, and nuts.

Clinical trials published by Frontiers in Nutrition found that intake of whole fiber-rich foods increased weight loss.

The trials indicated that a higher total fiber composite as well as a higher intake of vegetables and fruits resulted in greater weight loss.

Dr. Frank Hu, professor of Medicine at Harvard Medical School and professor of nutrition and epidemiology at the Harvard School of Public Health proclaims that “in addition to weight control, higher fiber diets can also help to prevent type 2 diabetes and cardiovascular diseases.” However, the professor emphasizes using dietary fiber instead of supplements.

  • May support weight loss the healthy way

  • May improve digestion and overall gut health

  • May help prevent diseases such as type 2 diabetes

  • May enhance satiety and appetite suppression

  • Can be found in most fruits and veggies

  • Dietary fiber may not be enough to cater to the body’s needs

  • More research is required to prove the potency of fiber supplements in comparison to dietary fiber

Best for:

Men looking for weight loss and more fiber to supplement their daily intake.


Fiber promotes weight loss, a healthy diet, and overall gut health.

What Are the Best Vitamins for Men's Weight Loss?

Vitamins have many benefits to our health among them is weight loss.

Vitamin B12

Vitamin B12, also cobalamin, naturally occurs in animal food sources such as fish, dairy products, meat, and shellfish.

A study in the Medicinski Glasnik journal established that low levels of vitamin B12 were associated with obesity and overweight.

However, there was no correlation between the vitamin with insulin resistance, metabolic syndrome, and gender.

According to /lient Bauer, M.D., a consultant in the Department of Internal Medicine at Mayo Clinic,

There is scanty proof that vitamin B12 shots help you lose weight.
Bauer suggests that if an individual wants to lose weight, a healthy lifestyle, healthy food in proper proportions, and regular physical activity is the way to go. Pros
  • May support weight loss and prevent obesity

  • May improve /liain function, nerve tissue, and red blood cells

  • May prevent fatigue and headaches associated with vitamin B12 deficiency

  • May boost energy production in the body

  • Absorption of vitamin B12 may be affected by some medications such as metformin

  • Dietary vitamin B12 may be superior to those provided by supplements

Best for:

Users looking to lose weight and enhance their vitamin B12 levels.

Final verdict:

Vitamin B12 is an essential vitamin with weight loss capabilities.

Men's Weight Loss Supplement Buyer's Guide

Now that you have an idea of what works and what doesn’t, here is our “how to buy guide.” When shopping for weight loss supplements consider:
  • Ingredients -

    pick out a weight loss product with a superior ingredient list.

    Supplements that lump up their ingredients in a proprietary blend and fail to mention the amount of each ingredient is not worth your time and money.

  • /liand -

    There are household names in the supplements world.

    Choose reputable /liands that have been tried and tested. Check out the company website to get a glimpse at their ingredients, scientific research, as well as return policies.

  • Customer reviews -

    Once you’ve set your eyes on a product, search for customer reviews as they shed light on the positives and negatives of the supplement.

    If you can get before and after pics, the better.

  • Realistic claims -

    Go for products that offer realistic results. For instance, a product that offers results in 60 days is a better product than one that offers overnight success.

  • Price range -

    A good men’s weight loss supplement is affordable, neither too expensive nor too cheap.

Are Weight Loss Supplements Safe?

Weight loss supplements are safe depending on where you purchase them from.

If you buy from a reputable /liand, chances are they are safe. No reputable /liand would want to jeopardize its business by scamming its customers.

Moreover, most good /liands hire professionals to formulate products. Rigorous lab tests are also conducted on ingredients to ensure consumer safety.

That said, side effects are inevitable which is why products should have a comprehensive ingredient label.

If you have an underlying health condition, make sure to consult your doctor before using any weight loss product.

Men's Weight Loss Supplement Alternatives

Apart from weight loss supplements, there are alternatives such as:

  • Weight loss pills –

    Contrave, Metformin, Tapamax, Rybelsus, Qsymia, and Xenical

  • Weight loss injections –

    Ozempic, Mounjaro, Saxenda, Wegova, Victoza, and Zepbound

Best Weight Loss Supplements for Men: Final Thoughts

Weight loss supplements for men come with different ingredients; some of which are scientifically effective while others, not so much.

This therefore requires users to do their own research on ingredients to get value for their money.

The ingredients in these products have unique mechanisms in which they target body fat in the body.

Some increase metabolism while others /lieak down fat deposits to produce energy.

The effectiveness of these products solely relies on the potency of the ingredients.

Although these supplements may work, their effectiveness relies on individual lifestyle.

A user who expects success from the products only may experience little to no results while the one who diets and exercises regularly may get optimal results.

To wrap up, weight loss supplements are more beneficial to users with a healthy lifestyle.

Therefore, before buying products for weight loss observe a healthy diet and exercise regularly.

This way you will only need supplements as the last resort.


  1. The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomized controlled trials
  2. Caffeine intake is related to successful weight loss maintenance
  3. The Effect of Green Tea Extract on Fat Oxidation at Rest and during Exercise: Evidence of Efficacy and Proposed Mechanisms
  4. The effects of magnesium supplementation on obesity measures in adults: a systematic review and dose-response meta-analysis of randomized controlled trials
  5. Magnesium intake is inversely associated with risk of obesity in a 30-year prospective follow-up study among American young adults
  6. Clinical Evidence and Mechanisms of High-Protein Diet-Induced Weight Loss
  7. Increased dietary fiber is associated with weight loss among Full Plate Living program participants
  8. Making one change — getting more fiber — can help with weight loss
  9. Association of vitamin B12 with obesity, overweight, insulin resistance and metabolic syndrome, and body fat composition; primary care-based study
  10. Are vitamin B-12 injections helpful for weight loss?

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